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Within these cells, AAS can biotransform into distinctive metabolites or bind to their cognate receptor: the androgen receptor. AAS as well as their metabolites can result in Unintended effects like acne vulgaris, hypertension, hepatotoxicity, dyslipidemia, testosterone deficiency, erectile dysfunction, gynecomastia, and cardiomyopathy. Exactly whe
AASs exert their consequences by activating androgen receptor (AR) signaling. Many areas of the body are associated as a result of existence of ARs in many tissues [12]. At ordinary physiologic amounts of testosterone androgen receptors are saturated as well as AASs effects could be a consequence of other mechanisms as an alternative to androgen re
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